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Poultry diseases and treatment

Dr. Mujeeb Ather Asst. Director (Pathologist)
Veterinary Biological Research Institute, Hyderabad .

LYMPHOID LEUCOSIS

Causative agent – RNA virus of sarcoma group.

SIGNS

  • Distended abdomen.
  • Loss of breast muscle with a prominent keel bone, shriveled and cyanotic

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comb.

  • Ascitis in a few birds.
  • Loss of appetite.
  • Decrease in egg production.

GROSS LESIONS

LIVER

  • Very enlarged extending up to the region.
  • Dark red in colour with fine white necrotic lesions distributed throughout the

organ.

  • Friable organ with thin margins.

SPLEEN

  • The organ is very much swollen, soft, friable and dark in colour.

 


Swollen spleen

KIDNEY

  • Slight enlargement of the organ with a few to many small tumerous growths.
  • Unilateral involvement is more common.
  • The organ is friable.

OVARY, LUNG AND PROVENTRICULUS

  • Presence of tumerous growth.

HEART

  • The lesions are rare.

HISTOPATHOLOGY

LIVER

  • Proliferative lesions with occupied uniform distribution of lymphoblasts

throughout the organ.

  • The tumour cells have moderately basophilic cytoplasm.
  • The nucleus is round and displaced.
  • Hepatic cells shows degenerative changes associated with necrosis

SPLEEN

  • Proliferation of lymphoblasts throughout the organ.

KIDNEY

  • Diffuse accumulation of large sized lymphoid cells in between the tubules and

glomeruli.

OVARY

  • Localized mild lymphoid cell infiltration.

HEART

  • Focal accumulation of lymphoid cells in intermuscular fibres and around the

coronary artery.

  • Muscle fibres with degenerative changes and necrosis.

LUNGS

  • Proliferation of lymphoblasts in bronchial mucosa with oedema.

PROVENTRICULUS

  • Uniformly distributed lymphoblasts with focal aggregation are seen,

cytoplasm is basophilic and the nucleus is vesicular.

DIAGNOSIS

  • By gross lesions.
  • Histopathology.
  • Isolation.
  • ELISA.